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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Bioorg Med Chem. 2015 Sep 25;23(21):6974–6992. doi: 10.1016/j.bmc.2015.09.036

Figure 8.

Figure 8

Inhibition of invasion and migration of MDA-MB-231 breast cancer cells by thiosemicarbazone analogues 1, 8, and 32. (a) Inhibition of MDA-MB-231 breast cancer cell invasion through Matrigel at 10 μM concentration of inhibitor. (b) Inhibition of MDA-MB-231 breast cancer cell invasion through Matrigel at 25 μM concentration of inhibitor. (c) Inhibition of MDA-MB-231 breast cancer cell migration at 10 μM concentration of inhibitor. (d) Inhibition of MDA-MB-231 breast cancer cell migration at 25 μM concentration of inhibitor. All values are normalized to 2% DMSO vehicle and are from a minimum of a triplicate of experiments (* p < 0.05, ** p < 0.01, *** p < 0.001).