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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Bioorg Med Chem. 2015 Sep 25;23(21):6974–6992. doi: 10.1016/j.bmc.2015.09.036

Scheme 1.

Scheme 1

Synthesis of benzoylbenzophenone thiosemicarbazone analogues. Reagents and conditions: (a) Thiosemicarbazide (TSC), TsOH, THF, reflux; (b) TSC, TsOH, MeOH, reflux; (c) EtOH, NaBH4, 0 °C.