Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Dec 3;44(6):e51. doi: 10.1093/nar/gkv1327

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 9. — QPID measurements explain in vivo binding differences between ATF1 and ATF3 to CRE half-sites. (A and B) Boxplots of affinity constants (1/K_d) in different binding site categories. ATF1 and ATF3 have higher affinities to sites they bound uniquely than sites bound by the other protein, unbound and controls. (C) Boxplots of affinity constant (1/K_d) differences between ATF1 and ATF3 in different binding sites categories. ATF1 has higher affinity in sites it binds uniquely than in sites bound by ATF3. (D and E) Fit of DNA shape features- based model to measured affinities. For each protein, multiple linear regression was used to infer a binding model based on DNA shape features. (F) Fit of DNA shape features-based model to difference in measured affinities. Multiple linear regression was used to infer a model for the difference in binding affinities.