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. 2016 Jan 20;44(6):2936–2948. doi: 10.1093/nar/gkw025

Table 2. Dissociation constants (Kd,BP and Kd,ZP2) for B-DNA and Z-DNA binding, equilibrium constant for B–Z transition (KBZ,1) and association/dissociation rate constants (kon,ZP and koff,ZP2) for Z-DNA binding of caZαPKZ with a 6-bp DNA.

DNA pH [NaCl] (mM) Kd,BP (μM) Kd,ZP2 (μM) KBZ,1 kon,ZP (×108 M−1s−1) koff,ZP2 (s−1)
dT(GC)3 6.0 10 0.028 ± 0.017 0.345 ± 0.079 0.87 ± 0.03 19.6 ± 1.2a 675 ± 43a
100 16.4 ± 0.8 8.76 ± 0.67 0.19 ± 0.02 1.56 ± 0.03b 1381 ± 30b
8.0 10 0.157 ± 0.021 0.129 ± 0.074 1.18 ± 0.03
100 5.41 ± 0.66 2.41 ± 0.37 0.18 ± 0.02
d(GC)3 8.0 10 5.18 ± 2.43 1.79 ± 0.95 0.11 ± 0.05

aFrom CPMG data with Pfree = 0.873.

bFrom CPMG data with Pfree = 0.891.