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. 2016 Jan 26;310(7):E484–E494. doi: 10.1152/ajpendo.00492.2015

Fig. 4.

Fig. 4.

Elevated levels of ceramides and diacylglycerols (DAGs) together with altered acylcarnitine profile in the liver of TFD mice indicate inefficient fat oxidation. Total hepatic DAG content (A), total hepatic ceramide content (B), fold changes in individual hepatic DAGs (C), fold changes in individual hepatic ceramides (D), and fold changes in individual hepatic acylcarnitines (E) relative to their respective age-matched controls. Mice were fed a TFD for either 8 or 24 wk. Values are means ± SE (n = 6–7/group). *P ≤ 0.05 between C vs. TFD-fed mice. #P ≤ 0.05 between 8- vs. 24-wk dietary treatments.