Fig. 1.—

Radical amino acid changes in selected sites across the cetacean phylogeny. Radical amino acid changes of positively selected sites in selected genes marked on different colors were labeled on the cetaceans phylogeny from branch a to m1. Parallel amino acid changes which occurred in selected genes HBA (blue), HBB (green), MB (red), EDN2 (orange), EDN3 (black), EDNRA (pink), EDNRB (purple), ADRA1D (purplish red), and AVP (yellow) among different lineages of cetaceans are shown on the right of the corresponding terminal branches, while letter in parentheses stand for the internal branches. Amino acid positions (numbers) and parallel changes at each position were listed in the right part of figure 1 corresponding to genes marked in different colors. Selected sites are indicated separately by vertical lines and stars.