Table 1.

List of adapters and primers used during HELP-tagging library preparation

Name	Sequence (5′-3′)
AE	5′-AcagtaatacgactcactatagggagaaggctCAAGCAGAAGACGGCATACGACAGCAG (AE_1)
	5′-p-CGCTGCTGTCGTATGCCGTCTTCTGCTTGagccttctccctatagtgagtcgtattactg*T (*T=Inverted-dT) (AE_2_Int_dT)
AS1	HT Adapter F 5′- ACACTCTTTCCCTACACGACGCTCTTCCGATCTTATGACG*T
	HT Adapter R 5′- pCGTCATAAGATCGGAAGAGCGTCGTGTAGGGAAAGAGTGT
AS2	HT Adapter F 5′- ACACTCTTTCCCTACACGACGCTCTTCCGATCTACATCTC*T
	HT Adapter R 5′- pGAGATGTAGATCGGAAGAGCGTCGTGTAGGGAAAGAGTGT
AS3	HT Adapter F 5′- ACACTCTTTCCCTACACGACGCTCTTCCGATCTCGGTACA*T
	HT Adapter R 5′- pTGTACCGAGATCGGAAGAGCGTCGTGTAGGGAAAGAGTGT
AS4	HT Adapter F 5′- ACACTCTTTCCCTACACGACGCTCTTCCGATCTGTCATGA*T
	HT Adapter R 5′- pTCATGACAGATCGGAAGAGCGTCGTGTAGGGAAAGAGTGT
PS	AATGATACGGCGACCACCGAGATCTACACTCTTTCCCTACACGACGCTCTTCCGATCT
PE	CAAGCAGAAGACGGCATACGACAGCAG