Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition of Hsp70 prevents platelet integrin-αIIbβ3 activation and fibrinogen binding. A and B: replicate samples of washed human platelets (2 × 108/ml, n = 5) were pretreated with PP2 (20 μM), MKT (20 μM), VER (20 μM), or vehicle alone (0.1% DMSO) prior to stimulation with 10 μg/ml CRP and flow cytometry analysis for integrin-αIIbβ3 activation as determined by PAC-1 binding or fluorescent fibrinogen (FITC-FG) binding. *P < 0.05.
