Table 1.

Serum and bronchoalveolar fluid cytokines in response to three doses of iloprost or saline placebo (acute treatment experiment)

	Serum			BALF
	LPS/Elastase + Placebo	LPS/Elastase + Iloprost	P Value	LPS/Elastase + Placebo	LPS/Elastase + Iloprost	P Value
IL1-β	49.2 ± 29.5	20.1 ± 5.3	0.1	7.5 ± 0.7	6.3 ± 2.7	0.51
IL-2	14.6 ± 2.2	11.5 ± 1.8	0.07	2.9 ± 1.8	4.8 ± 1.1	0.14
IL-4	22.1 ± 10.1	23.6 ± 7.7	0.82	6.6 ± 1.1	12.4 ± 4.5	0.09
IL-5	11.3 ± 0.7	2.5 ± 0.7	0.0001	2.7 ± 0.6	3.0 ± 1.3	0.67
IL-10	10.2 ± 10.7	7.7 ± 7.1	0.71	4.6 ± 2.0	4.8 ± 2.1	0.93
GM-CSF	63.5 ± 34.0	18.9 ± 17.4	0.07	4.7 ± 1.5	4.3 ± 2.7	0.84
IFN-γ	83.4 ± 14.3	11.1 ± 8.6	0.0004	2.2 ± 0.3	2.6 ± 0.6	0.31
TNF-α	7.6 ± 1.8	24.1 ± 12.5	0.04	8.0 ± 2.9	8.9 ± 1.8	0.65

All data are presented as means ± SD. All units are given in picograms per milliliter. BALF, bronchoalveolar fluid. Comparisons were made using unpaired t-tests. n = 10 for LPS/elastase + placebo, and n = 9 for LPS/elastase + iloprost.