Table 1.

Characteristics of male participants at EDIC year 10 (n=508), means (SD) or n (%).

Total testosterone (nmol/l)	20.9 (7.1)
Bioavailable testosterone (nmol/l)	0.34 (0.08)
Sex hormone binding globulin (nmol/l)	55.3 (23.6)
Age (years)	45 (6)
Randomization arm (n,%)
Conventional	259 (51%)
Intensive	249 (49%)
Primary cohort (n,%)	257 (51%)
Current smoking (n,%)	59 (12%)
Current alcohol use (n,%)	260 (51%)
Body mass index (n,%)
< 25 kg/m2	173 (34%)
25-29.9 kg/m2	288 (57%)
≥30 kg/m2	47 (9%)
Time-weighted body mass index (kg/m2)	26.1 (2.8)
Time-weighted insulin dose (units/kg/day)	0.7 (0.2)
Time-weighted DCCT/EDIC HbA1c (mmol/mol)	64 (11)
Anti-hypertensive medication use (%)	279 (55%)
Time-weighted systolic blood pressure (mm Hg)	120 (8)
Time-weighted low-density lipoprotein cholesterol (mg/dl)	114 (23)
Time-weighted high-density lipoprotein cholesterol (mg/dl)	49 (11)
History of albumin excretion ratio ≥ 300 mg/24 hours (n, %)	49 (10%)
Left ventricular mass index (g/m2)	76.5 (12.3)
End-diastolic volume (ml/m2)	73.3 (12.6)
End-systolic volume (ml/m2)	29.2 (7.8)
Stroke volume index (ml/m2)	44.1 (8.0)
Ejection fraction (%)	60.3 (6.3)
Cardiac output (L• min-1•m-2)	3.1 (0.6)
Left ventricular mass/end-diastolic volume (mg/ml)	1.1 (0.2)