ND2PXL cytotoxicity in vitro is dependent on MMP9 activity. A: Zymogram of conditioned media from LLCRSV and LLCMMP9 cells. B: Viability of LLCRSV and LLCMMP9 cells, with low and high MMP9 expression, respectively, and LLCMMP9 cells in the, presence of 10 QM GM6001 and vehicle-treated cells, each after 48 hours of treatment with 50 nM ND2PXL.