Table 5.
Comparison of CDC and Inbios CSF test results based on JEV and DENV MAC-ELISA testing only
| CDC JE+ | CDC DEN+ | CDC NEG | Total | ||||
|---|---|---|---|---|---|---|---|
| JEV+/DENV− | JEV+/DEN+* | JEV−/DENV+ | JEV+/DEN+* | JEV/DEN− | |||
| JE Detect + DEN Detect | Inbios JE+/DEN− | 12 | 3† | 1 | 0 | 0 | 16 |
| Inbios JE+/DEN+ | 0 | 8 | 0 | 0 | 0 | 8 | |
| Inbios JE−/DEN− | 0 | 1 | 5 | 3 | 42 | 51 | |
| Total | 12 | 12 | 6 | 3 | 42 | 75 | |
CDC = Centers for Disease Control and Prevention; CSF = cerebrospinal fluid; DEN Detect = DEN Detect™ MAC-ELISA; DENV = dengue virus; EQ = equivocal; JE = Japanese encephalitis; JE Detect = JE Detect™ MAC-ELISA; JEV = Japanese encephalitis virus; MAC-ELISA = IgM antibody-capture enzyme-linked immunosorbent assay; NEG = negative.
*
Differential diagnosis determined by 4-fold higher neutralization titer.
†
DEN Detect EQ results were coded as NEG.