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. Author manuscript; available in PMC: 2016 Apr 7.
Published in final edited form as: Obstet Gynecol. 2009 Dec;114(6):1189–1196. doi: 10.1097/AOG.0b013e3181c15064

Table 3.

Detection Rate for a 5% False-Positive Rate With Standard Screening Policies and With Risk Modified by Genetic Sonogram Result

Policy Standard After Sonogram
Combined 81 90*
Quadruple 81 90
Integrated 93 98
Stepwise 97 98
Contingent 95 97
Stepwise sonogram 90
Contingent sonogram 90

Data are %.

*

Not interpreting the test until the sonogram is complete.

Replacing the second-stage quadruple markers with the sonogram.