Table 1. Human (h)AQP4284-299 Alanine Scanning Peptides.
The immunogenic region of hAQP4281-300, hAQP4284-299, was utilized to generate alanine scanning peptides at which each peptide sequence has a single alanine residue mutation.
| Peptide | Amino Acid Sequence |
|---|---|
| Human 284–299 | RSQVETDDLILKPGVV |
| Mouse 284–299 | RSQVETEDLILKPGVV |
| R284A | ASQVETDDLILKPGVV |
| S285A | RAQVETDDLILKPGVV |
| Q286A | RSAVETDDLILKPGVV |
| V287A | RSQAETDDLILKPGVV |
| E288A | RSQVATDDLILKPGVV |
| T289A | RSQVEADDLILKPGVV |
| D290A | RSQVETADLILKPGVV |
| D291A | RSQVETDALILKPGVV |
| L292A | RSQVETDDAILKPGVV |
| I293A | RSQVETDDLALKPGVV |
| L294A | RSQVETDDLIAKPGVV |
| K295A | RSQVETDDLILAPGVV |
| P296A | RSQVETDDLILKAGVV |
| G297A | RSQVETDDLILKPAVV |
| V298A | RSQVETDDLILKPGAV |
| V299A | RSQVETDDLILKPGVA |