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. 2016 Apr 6;57(4):1578–1587. doi: 10.1167/iovs.15-17894

Figure 1.

Figure 1

Rejection of corneal grafts placed into WT HSV-1–infected high-risk hosts. Wild-type BALB/c mice were infected with HSV-1 6 weeks (42 days) prior to placement of corneal grafts, which were secured with a continuous suture in this set of experiments. (a) Clinical appearance of the vascularized corneal graft bed at 6 week post HSV-1 infection; (b) corneal graft survival in vascularized corneal beds in syngraft HSK (n = 15), allograft HSK (n = 20), and allograft HSK treated with ACV (n = 10) groups compared with WT, noninfected BALB/c recipients transplanted with allograft (n = 20); (c) clinical appearance of rejecting corneal allograft placed into vascularized corneal graft bed (day 3 post allograft); (d) corneal graft survival in previously infected but not vascularized (at 6 weeks post infection [p.i.]) graft beds for both allo- and syngrafts compared with WT, noninfected BALB/c recipient transplanted with allograft.