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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: J Immunol. 2016 Mar 2;196(7):3079–3087. doi: 10.4049/jimmunol.1502061

Fig. 1. Antibody responses to EnxB-vaccine are inversely correlated to the level of circulating HBs.

Fig. 1

(A) Serum levels of HBs in AAV/HBV carrier mice were monitored by ELISA after vaccination with EnxB. HBs values are presented as a nanogram per milliliter and are expressed as means ± SD of three mice in each time point. (B) Ayw subtype-specific anti-HBs antibody responses in AAV/HBV carrier mice were monitored by ELISA at indicated time points (n=3). (C) Serum HBs in HDI/HBV mice after EnxB- vaccination was monitored by ELISA (n=4). (D) Anti-HBs antibody responses in HDI/HBV mice were monitored by ELISA at indicated time points post vaccination (n=4). The arrows indicate the time points of EnxB vaccination. High, high antigenemia; Low, low antigenemia; NTC, no treatment control; EnxB, s.c. vaccinated with EngerixB; ND, not detected; NS, not significant; *P < 0.05, **P < 0.01, and ***P < 0.001versus corresponding control mice (throughout all figures). The data presented are representative of three independent experiments.