Table 2. Allograft function outcomes for liver transplant recipients, based on APOL1 genotype of African American deceased donors.
| APOL1 renal-risk variant number in liver donors | ||||
|---|---|---|---|---|
| Variable | APOL1 = 0 (N = 247) | APOL1 = 1 (N = 300) | APOL1 = 2 (N = 92) | P-value |
| Allograft failure within 15 days (Yes) | 3 (1.2%) | 7 (2.3%) | 0 (0.0%) | 0.25 |
| Allograft failure within 6 months (Yes) | 8 (3.2%) | 15 (5.0%) | 1 (1.1%) | 0.19 |
| Allograft failure within 1 year (Yes) | 11 (4.5%) | 18 (6%) | 4 (4.3%) | 0.67 |
| Allograft failure, total (Yes) | 20 (8.1%) | 23 (7.7%) | 6 (6.5%) | 0.89 |
| Recipient death (Yes) | 67 (27.1%) | 98 (32.7%) | 20 (21.7%) | 0.09 |
| Death with functioning allograft (Yes) | 53 (21.5%) | 72 (24%) | 12 (13%) | 0.08 |
| Allograft survival (months)* | 39.9 (30.1) 36 | 40.4 (31.1) 36 | 49.1 (33.5) 48 | 0.07 |
* The numbers are: mean (standard deviation) and median.