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. 2016 Apr 7;11(4):e0152761. doi: 10.1371/journal.pone.0152761

Table 3. Different time components from first care seeking visit to MDR-TB treatment initiation in SSm- patients.

Culture-based algorithm LPA-based algorithm p-value
LJ (N = 67) MGIT + LPA (n = 48) LJ+LPA (n = 12)
Median time from first care seeking visit to first microscopy (days, range) IQR 1 (0–770) IQR: 0–63.5 7.5 (0–209) IQR: 1.8–29 25 (6–168) IQR: 8.8–45 LJ vs. MGIT+LPA: p = 0.105 LJ vs. LJ+LPA: p = 0.020
Median time from first microscopy to sputum used for DST or LPA 2 (0–770) IQR: 0–74.8 7.5 (0–256) IQR: 1–29 25 (6–168) IQR: 8.8–45 LJ vs. MGIT+LPA: p = 0.322 LJ vs. LJ+LPA: p = 0.025
Laboratory turn-around time 74 (22–125) IQR: 64.3–84 28.5 (9–85) IQR: 23–35.3 64 (22–86) IQR: 54–72.3 LJ vs. MGIT+LPA: p<0.001 LJ vs. LJ+LPA: p = 0.020
Median time from DST or LPA result to treatment (days, range) 28 (6–262) IQR: 15–47.5 15 (5–493) IQR: 10–24.8 17 (13–42) IQR: 17–29.5 LJ vs. MGIT+LPA: p<0.001 LJ vs. LJ+LPA: p = 0.716
Overall median time from 1st visit to treatment 140 (29–858) IQR: 99.5–216.5 62 (24–579) IQR: 50.3–84 113 (67–253) IQR: 88.5–131.8 LJ vs. MGIT+LPA: p<0.001 LJ vs. LJ+LPA: p = 0.037