Table 3. Genotype Effects on N100 Event-Related Potential (Cz).
| Parameter | DF | F-Value | Original P-Value | Beta |
|---|---|---|---|---|
| Unconstrained Genetic Model | ||||
| Sex | 1 | 10.39 | 0.0013 | Females 0.22 |
| Study Center | 6 | 26.89 | <0.0001 | -0.08 (AC) |
| 0.39 (BE) | ||||
| 0.66 (BN) | ||||
| 0.09 (DU) | ||||
| -0.24 (ER) | ||||
| -0.34 (MA) | ||||
| 0.00 (MZ) | ||||
| Genotype | 2 | 16.06 | <0.0001 | -0.23 (TT) |
| -0.07 (TC) | ||||
| 0.00 (CC) | ||||
| Sex*Genotype | 2 | 1.58 | 0.2072 | Females |
| -0.18 (TT) | ||||
| -0.01 (TC) | ||||
| 0.00 (CC) | ||||
| Recessive Genetic Model | ||||
| Sex | 1 | 6.12 | 0.0134 | Females 0.21 |
| Study Center | 6 | 26.88 | <0.0001 | -0.08 (AC) |
| 0.38 (BE) | ||||
| 0.66 (BN) | ||||
| 0.09 (DU) | ||||
| -0.24 (ER) | ||||
| -0.35 (MA) | ||||
| 0.00 (MZ) | ||||
| Genotype | 1 | 30.46 | <0.0001 | -0.18 |
| Sex*Genotype | 1 | 3.11 | 0.0782 | Females-0.17 |
Linear Regression models after stepwise backward selection of variables (n = 1,705 subjects). Top: Unconstrained genetic model (DF = 11; p < .0001; R² = 0.11; β = 0.95). Bottom: Recessive genetic model (DF = 9; p < .0001; R² = 0.11; β = 0.90). AC = Aachen, BE = Berlin, BN = Bonn, DU = Düsseldorf, ER = Erlangen, MA = Mannheim, MZ = Mainz.