Table 1. Baseline Patient Characteristics.
| Pretreatment characteristics | Value |
|---|---|
| Age (y) | 59 (27-82) |
| WBC (K/μL) | 92.4 (7.9-363) |
| ALC (K/μL) | 79.5 (3.7-323.9) |
| Hemoglobin (g/dL) | 12.8 (8.5-15.2) |
| Platelets (K/μL) | 156 (31-353) |
| β2-microglobulin (mg/L) | 3.8 (1.6-10.1) |
| Gender | |
| Male | 52 (80) |
| Female | 13 (20) |
| Rai stage | |
| 0-II | 46 (71) |
| III-IV | 19 (29) |
| CD38 expression (n=61) | |
| <30% | 43 (70) |
| ≥30% | 18 (30) |
| IGHV mutational status (n=62) | |
| Mutated (≥2%) | 16 (26) |
| Unmutated (<2%) | 46 (74) |
| Zap-70 flow (n=39) | |
| Negative (<20%) | 18 (46) |
| Positive (≥20%) | 21 (54) |
| FISH, bone marrow (n=48) | |
| Negative | 14 (29) |
| Single abnormality | |
| del13q | 10 (21) |
| Trisomy 12 | 8 (17) |
| del11q | 3 (6) |
| Multiple abnormalities | |
| del11q and del13q | 10 (21) |
| del11q and del17p | 1 (2) |
| Trisomy 12 and del13q | 2 (4) |
Values are median (range) or n (%)
WBC, white blood cells; ALC, absolute lymphocyte count; IGHV, immunoglobulin variable heavy chain; FISH, fluorescent in situ hybridization