Table 2. Unadjusted logistic regression and C-statistics for the association of CVD Risk factors and risk scores with stroke.
Risk Factors and Risk scores | Odds ratio (95% C I) | p | C-statistics (95% CI) | p |
---|---|---|---|---|
Age | 1.05(1.04-1.07) | <0.001 | 0.67(0.62-0.72) | <0.001 |
Sex (male) | 1.62(1.13-2.32) | 0.01 | 0.56(0.51-0.61) | 0.02 |
Total cholesterol | 1.03(1.03-1.04) | <0.001 | 0.86(0.81-0.90) | <0.001 |
HDL cholesterol | 1.04(1.01-1.07) | 0.02 | 0.63(0.52-0.75) | 0.02 |
Systolic Blood pressure | 0.99(0.99-1.00) | 0.05 | 0.56(0.51-0.62) | 0.03 |
Diastolic Blood pressure | 0.99(0.98-1.00) | 0.40 | 0.63(0.52-0.75) | 0.02 |
Smoking | 1.17(0.58-2.36) | 0.66 | 0.51(0.45-0.56) | 0.84 |
Alcohol | 2.77(1.45-5.32) | 0.002 | 0.63(0.53-0.68) | 0.01 |
Diabetes | 1.91(1.13-3.21) | 0.02 | 0.54(0.49-0.60) | 0.10 |
FRS* | 1.00(0.94-1.06) | 0.89 | 0.56(0.44-0.67) | 0.39 |
ORS | 1.02(0.95-1.10) | 0.53 | 0.54(0.41-0.67) | 0.55 |
Right CIMT | 8.01(2.96-21.72) | <0.001 | 0.63(0.56-0.69) | <0.001 |
Left CIMT | 13.98(4.98-39.26) | <0.001 | 0.67(0.61-0.73) | <0.001 |
Average CIMT | 20.04(6.24-64.23) | <0.001 | 0.66(0.60-0.73) | <0.001 |
Conventional Risk Factors (CRF) | 0.83(0.68-0.97) | 0.003 | ||
CRF with Right CIMT | 0.84(0.65-1.00) | 0.005 | ||
CRF with Left CIMT | 0.85(0.69-1.00) | 0.004 | ||
CFR with Average CIMT | 0.87(0.80-0.94) | <0.001 |
CIMT- Carotid intima media thickness
FRS*- Framingham risk score FRS without calibration factor
ORS- Omnibus risk score
CRF- Conventional Risk Factors (age, sex, alcohol, cholesterol, diabetes, smoking, systolic blood pressure, diastolic blood pressure)