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Simulation tests and Parameters
| Test Parameter | Altering OR | Altering Proportion of Risk Variants |
|---|---|---|
| Number of Simulations | 1000 | 1000 |
| Sample Size | 1000 cases and 1000 controls | 1000 cases and 1000 controls |
| Proportion of Causal Variants (n=100) | 40%, 10% | 40% |
| Disease Prevalence | 5% | 5%, 50% |
| Odds Ratio (OR) | 1.5, 2.0, 3.0 | 3.0 |
| Proportion of Risk Variants | 50%, 100% | 25%, 40%, 50%, 60%, 75%, 100% |
| Variant Weighting | No Weighting, Madsen and Browning | No Weighting, Madsen and Browning |
