Table 2.
Clinical and Biochemical Characteristics: Beer-Sheva Cohort (N=69)
| Lean | Overweight | Obese | |||
|---|---|---|---|---|---|
| BMI≤25 | 25<BMI<30 | BMI≥30 | Entire group | P ANOVA | |
| n | 14 | 11 | 44 | 69 | |
| Sex (male/female) | 4/10 | 6/5 | 6/38 | 16/53 | |
| Age (y) | 44.6 ± 5.3 | 47.5 ± 5.7 | 42.7 ± 2.3 | 43.9 ± 2.0 | NS |
| BMI (kg/m2) | 22.4 ± 0.6 | 27.7 ± 0.2 | 40.6 ± 0.8 | 34.8 ± 1.1 | <0.01 |
| Waist circumference (cm) | 68.9 ± 6.7 | 92.9 ± 2.9 | 114.1 ± 2.7 | 100.4 ± 3.3 | <0.01 |
| SBP (mm Hg) | 120.5 ± 3.4 | 121.8 ± 2.9 | 133.0 ± 2.6 | 128.3 ± 2.0 | <0.05 |
| DBP (mm Hg) | 73.1 ± 2.0 | 76.0 ± 2.0 | 82.3 ± 1.9 | 79.4 ± 1.4 | <0.05 |
| Triglycerides (mg/dL) | 105.3 ± 14.9 | 113.3 ± 17.6 | 158.0 ± 12.3 | 139.7 ± 9.1 | <0.05 |
| HDL (mg/dL) | 52.5 ± 3.6 | 41.6 ± 5.9 | 49.6 ± 2.2 | 48.7 ± 1.8 | <0.05 |
| FPG (mg/dL) | 95.2 ± 5.5 | 87.3 ± 3.5 | 104.1 ± 6.7 | 99.5 ± 4.4 | NS |
| HbA1c (%) | 5.6 ± 0.2 | 5.6 ± 0.2 | 5.9 ± 0.2 | 5.8 ± 0.1 | NS |
| hsCRP | 0.6 ± 0.4 | 0.9 ± 0.5 | 1.2 ± 0.3 | 1.1 ± 0.2 | <0.05 |
| Fasting insulin (pmol/L) | 3.2 ± 0.5 | 4.7 ± 0.9 | 12.7 ± 1.4 | 9.3 ± 1.1 | 0.001 |
| HOMA-IR | 0.8 ± 0.2 | 1.1 ± 0.2 | 3.3 ± 0.4 | 2.4 ± 0.3 | <0.001 |
BMI, body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HbA1c, hemoglobin A1c ; HDL, high density lipoprotein; HOMA-IR, homeostatic model assessment of insulin resistance; hsCRP, high sensitivity c-reactive protein; SBP, systolic blood pressure; NS, nonsignificant (P>0.05).