. Author manuscript; available in PMC: 2017 Mar 25.

Published in final edited form as: Kidney Blood Press Res. 2016 Mar 25;41(2):208–221. doi: 10.1159/000443424

Table 1.

Effects of MSU i.r. infusion on renal function in mice receiving vehicle and caspase-1 inhibitor

		Control	0.1	0.3	0.6	Post
U•V	Vehl	14.60±0.47	9.82±1.56	6.58±2.00^*	4.65±1.79^*	5.28±2.30^*
(µl/min/gkw)	YVAD	15.80±1.34	14.91±1.75	14.27±1.66	12.10±1.50	12.72±1.40
U_Na•V	Vehl	3.87±0.31	2.59±0.34	1.64±0.47^*	1.17±0.41^*	1.39±0.39^*
(µmol/min/gkw)	YVAD	4.01±0.39	3.65±0.26	3.55±0.28	2.97±0.39	3.40±0.46
U_K•V	Vehl	1.61±0.32	1.42±0.19	1.41±0.20	1.39±0.21	1.52±0.19
(µmol/min/gkw)	YVAD	1.50±0.11	1.53±0.11	1.49±0.09	1.45±0.08	1.48±0.11

U•V: urine volume, U_Na•V; urinary sodium excretion, U_K•V; urinary potassium excretion. Values are arithmetic means ± SEM (n=6 mice per group),

P<0.05 vs. control periods.