Skip to main content
. Author manuscript; available in PMC: 2017 Mar 25.
Published in final edited form as: Kidney Blood Press Res. 2016 Mar 25;41(2):208–221. doi: 10.1159/000443424

Table 2.

Effects of MSU i.r. infusion on renal function in WT and Nlrp3 KO mice

Control 0.1 0.3 0.6 Post
U•V WT 15.62±1.93 13.30±2.10 7.75±1.22* 7.51±1.61* 9.57±2.24
(µl/min/gkw) Nlrp3KO 17.98±2.71 16.76±2.99 16.00±3.18 16.02±3.27 16.45±2.91
UNa•V WT 5.23±0.52 4.60±0.55 2.75±0.25* 3.08±0.53* 3.83±0.55
(µmol/min/gkw) Nlrp3KO 5.08±0.26 4.87±0.28 4.56±0.17 4.52±0.22 4.71±0.28
UK•V WT 1.73±0.23 1.69±0.22 1.65±0.12 1.65±0.20 1.73±0.23
(µmol/min/gkw) Nlrp3KO 1.67±0.28 1.65±0.22 1.56±0.20 1.66±0.23 1.61±0.20

U•V: urine volume, UNa•V; urinary sodium excretion, UK•V; urinary potassium excretion. Values are arithmetic means ± SEM (n=6 mice per group)

*

P<0.05 vs. control periods.