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. Author manuscript; available in PMC: 2017 Mar 25.
Published in final edited form as: Kidney Blood Press Res. 2016 Mar 25;41(2):208–221. doi: 10.1159/000443424

Table 3.

Effect of MSU i.r. infusion on renal function in WT and Asc KO mice

Control 0.1 0.3 0.6 Post
U•V WT 15.72±1.96 12.47±2.17 7.28±1.26* 6.36±1.27* 8.39±2.13
(µl/min/gkw) ASC KO 15.91±1.02 15.69±1.10 14.60±1.10 14.27±1.09 15.21±1.34
UNa•V WT 4.21±0.21 3.37±0.28 2.21±0.18* 1.95±0.24* 2.51±0.29
(µmol/min/gkw) ASC KO 5.02±0.27 5.03±0.29 4.76±0.34 4.65±0.36 4.88±0.34
UK•V WT 1.77±0.21 1.77±0.21 1.68±0.11 1.71±0.19 1.79±0.21
(µmol/min/gkw) ASC KO 1.24±0.15 1.22±0.17 1.14±0.14 1.13±0.12 1.21±0.16

U•V: urine volume, UNa•V; urinary sodium excretion, UK•V; urinary potassium excretion. Values are arithmetic means ± SEM (n=6 mice per group),

*

P<0.05 vs. control periods.