Table 7. Differences between N categories (IASLC/ITMIG TNM staging proposal).
| HR vs. adjacent N category | CIR, R0 (67/1,060)* |
OS, R0 (23/1,085)* |
OS, any R (39/1,198)* |
|||||
|---|---|---|---|---|---|---|---|---|
| HR | P | HR | P | HR | P | |||
| N1 vs. N0 | 15.66 | 0.000 | 6.817 | 0.062 | 13.034 | 0.000 | ||
| N2 vs. N0 | 10.99 | 0.018 | 0.050 | 0.876 | 14.074 | 0.000 | ||
| N2 vs. N1 | 0.893 | 0.922 | 0.033 | 0.737 | 0.515 | 0.559 | ||
| N1 + N2 vs. N0 | 14.77 | 0.000 | 4.968 | 0.119 | 8.617 | 0.000 | ||
Hazard ratios and statistical differences (χ2) by Cox proportional hazards regression models, adjusted by diagnosis. *, number of events/total number of patients in entire data set for the particular analysis. IASLC, the International Association for the Study of Lung Cancer; ITMIG, the International Thymic Malignancies Interest Group; HR, hazard ratio; CIR, cumulative incidence of recurrence; R0, complete resection; OS, overall survival.