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. 2016 Apr;8(4):646–655. doi: 10.21037/jtd.2016.03.01

Table 2. Patient characteristics and CT findings in TETs.

Patient characteristics and CT findings Masaoka-Koga clinical stage
P value
I (n=63) II (n=32) III (n=32) IV (n=11)
Gender (male/female) 31/32 14/18 18/14 7/4 NS*
Myasthenia gravis (yes/no) 10/53 5/27 3/29 0/11 NS*
Age (mean value, years) 53.2 58.6 52.6 50.9 NS**
Size (mean value, cm)
   X-axis diameter 5.5 4.5 6.6 5.1 0.005**
   Y-axis diameter 3.8 3 4.4 3 0.004**
   Z-axis diameter 6.4 4.7 7.1 5.9 0.005**
Shape (round/lobulated/irregular) 29/29/5 10/16/16 4/7/21 2/3/6 0.000*
Contour (smooth/partial smooth/unsmooth) 31/31/1 6/24/2 0/21/11 1/6/4 0.000*
Internal density (homogeneous/heterogeneous) 33/30 16/16 9/23 3/8 NS*
Enhancement pattern (homogeneous/heterogeneous) 15/48 8/24 1/31 3/8 0.041*
Calcification (yes/no) 12/51 8/24 8/24 3/8 NS*
Infiltration of surrounding fat (yes/no) 29/34 29/3 29/3 11/0 0.000*
Invasion of mediastinal pleura (yes/no) 24/39 15/17 29/3 9/2 0.000*
Invasion of lung (yes/no) 7/56 1/31 22/10 7/4 0.000*
Invasion of pericardium (yes/no) 4/59 2/30 22/10 5/6 0.000*
Invasion of great vessels (yes/no) 4/59 0/32 15/17 6/5 0.000*
Invasion of phrenic nerve or elevated hemidiaphragm (yes/no) 1/62 1/31 11/21 3/8 0.000*
Presence pleural effusion (yes/no) 2/61 1/31 2/30 3/8 0.000*
Mediastinal lymph node enlargement (yes/no) 0/63 0/32 1/31 1/10 NS*
Pleura and/or pulmonary nodule (yes/no) 0/63 0/32 0/32 5/6 0.000*

NS, not significant; *, P values were calculated using the chi-square test or the Fisher exact test for categorical variables; **, P values were calculated using the Mann-Whitney U test for continuous variables; CT, computed tomography; TET, thymic epithelial tumor.