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. 2016 Apr 8;10:116. doi: 10.3389/fnins.2016.00116

Table 2.

Summary of results on neural implant studies for sensory feedback restoration.

Rossini et al., 2010 Raspopovic et al., 2014 Ortiz-Catalan et al., 2014a Tan et al., 2014
Number of subjects 1 1 1 2
Experimental period 4 weeks 4 weeks up to 16 months up to 24 months
Electrodes tf-LIFEs (thin-film Longitudinally-implanted Intra Fascicular Electrodes) TIMEs (transversal intrafascicular multichannel electrodes) Cuff electrode (Ardiem Medical) FINE (flat interface nerve electrodes) Cuff electrode (Ardiem Medical)
Number of electrodes 4 4 1 Subject 1: 2 FINEs, 1 cuff Subject 2: 2 FINEs
Nerves Median and ulnar nerves Median and ulnar nerves Ulnar nerve Subject 1: medial and ulnar nerves Subject 2: medial and radial nerves
Trains of pulses Rectangular cathodal pulses Rectangular cathodal pulses Single active charge-balanced biphasic pulse Square electrical pulses
Frequency 10–100 Hz 50 Hz 8–20 Hz 10–125 Hz
Current 10–100 μA maximum stimulation current: 240 μA (at 100 μs) for the index finger and 160 μA(at50 μs) for the little finger. 30–50 μA 1.1–2 mA
Pulse width 10–300 μs 24–60 μs
Charge 0.1–4 nC Median nerve: 14-24 nC Ulnar nerve: 4-8 nC 100-180 μA Subject 1: 40.7–95.5 nC Subject 2: 95–141 nC
Elicited hand areas Figure 3A Figure 3B Figure 3C Figures 3D–E
Grasping task Power grip, pinch grip, little finger flexion Palmar grasp, pinch grasp, ulnar grasp Tripod grasp during arm oscillation, power grasp in different limb position