Table 2.
Rossini et al., 2010 | Raspopovic et al., 2014 | Ortiz-Catalan et al., 2014a | Tan et al., 2014 | |
---|---|---|---|---|
Number of subjects | 1 | 1 | 1 | 2 |
Experimental period | 4 weeks | 4 weeks | up to 16 months | up to 24 months |
Electrodes | tf-LIFEs (thin-film Longitudinally-implanted Intra Fascicular Electrodes) | TIMEs (transversal intrafascicular multichannel electrodes) | Cuff electrode (Ardiem Medical) | FINE (flat interface nerve electrodes) Cuff electrode (Ardiem Medical) |
Number of electrodes | 4 | 4 | 1 | Subject 1: 2 FINEs, 1 cuff Subject 2: 2 FINEs |
Nerves | Median and ulnar nerves | Median and ulnar nerves | Ulnar nerve | Subject 1: medial and ulnar nerves Subject 2: medial and radial nerves |
Trains of pulses | Rectangular cathodal pulses | Rectangular cathodal pulses | Single active charge-balanced biphasic pulse | Square electrical pulses |
Frequency | 10–100 Hz | 50 Hz | 8–20 Hz | 10–125 Hz |
Current | 10–100 μA | maximum stimulation current: 240 μA (at 100 μs) for the index finger and 160 μA(at50 μs) for the little finger. | 30–50 μA | 1.1–2 mA |
Pulse width | 10–300 μs | – | – | 24–60 μs |
Charge | 0.1–4 nC | Median nerve: 14-24 nC Ulnar nerve: 4-8 nC | 100-180 μA | Subject 1: 40.7–95.5 nC Subject 2: 95–141 nC |
Elicited hand areas | Figure 3A | Figure 3B | Figure 3C | Figures 3D–E |
Grasping task | Power grip, pinch grip, little finger flexion | Palmar grasp, pinch grasp, ulnar grasp | Tripod grasp during arm oscillation, power grasp in different limb position |