Table 1.
Peptide | Producing bacteria | Amino acids sequence (Nter–Ctter) | MIC (μM) | |
---|---|---|---|---|
Group 1 | Warnericin RK | S. warneri | MQFITDLIKKAVDFFKGLFGNK | 0.3 |
δ-Lysin I* | S. warneri | MAADIISTIGDLVKLIINTVKKFQK | 1.08 | |
δ-Lysin II | S. warneri | MTADIISTIGDFVKWILDTVKKFTK | 0.54 | |
δ-Hemolysin | S. aureus | MAQDIISTIGDLVKWIIDTVNKFTKK | 1.05 | |
Ggi I | S. haemolyticus | MQKLAEAIAAAVSAGQDKDWGKMGTSIVGIVENGITVLGKIFGF | 4.15 | |
SLUSH C | S. lugdunensis | MDGIFEAISKAVQAGLDKDWATMGTSIAEALAKGVDFIIGLFH | 5.16 | |
SLUSH A | S. lugdunensis | MSGIVDAITKAVQAGLDKDWATMATSIADAIAKGVDFIAGFFN | 11.28 | |
Group 2 | PSMα | S. epidermidis | MADVIAKIVEIVKGLIDQFTQK | 0.63 |
δ-Hemolysin | S. epidermidis | MMAADIISTIGDLVKWIIDTVNKFKK | 1.59 | |
PSMβ | S. epidermidis | MSKLAEAIANTVKAAQDQDWTKLGTSIVDIVESGVSVLGKIFGF | 2.69 | |
H2U* | S. cohnii | MDFIIDIIKKIVGLFTGK | 3.04 | |
Ggi II | S. haemolyticus | MEKIANAVKSAIEAGQNQDWTKLGTSILDIVSNGVTELSKIFGF | 13.23 | |
Haemo 3 | S. haemolyticus | n.d. | 1.38 |
Minimum inhibitory concentrations were determined against L. pneumophila Lens and for the formylated forms of the peptides except for the peptides indicated by *.