Table I. Top gene sets over-representing proteins up-regulated by brusatol treatment.
| Gene set name [# Genes (K)] | Description | # Genes in overlap (k) | p value | FDR q-value |
|---|---|---|---|---|
| KEGG_RIBOSOME [88] | Ribosome | 21 | 7.93 e−49 | 8.21 e−45 |
| REACTOME_PEPTIDE_CHAIN_ELONGATION [153]α | Genes involved in peptide chain elongation | 20 | 1.16 e−40 | 6.02 e−37 |
| REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION [169] | Genes involved in influenza viral RNA transcription and replication | 20 | 9.62 e−40 | 2.73 e−36 |
| REACTOME_TRANSLATION [222] | Genes involved in translation | 21 | 1.05 e−39 | 2.73 e−36 |
| REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION [176] | Genes involved in 3′-UTR-mediated translational regulation | 20 | 2.27 e−39 | 3.91 e−36 |