Table 2. GO-dysregulated.
The top 15 up- and downregulated GO terms.
| GO-ID | GO-name | Enrichment | P-value |
|---|---|---|---|
| Upregulated GOs by GO analysis | |||
| GO:0043066 | Negative regulation of apoptotic process | 5.274431709 | 5.53034E−12 |
| GO:0032496 | Response to lipopolysaccharide | 8.108054973 | 1.51933E−11 |
| GO:0006954 | Inflammatory response | 8.099023444 | 2.11218E−10 |
| GO:0007165 | Signal transduction | 5.49328365 | 2.53815E−10 |
| GO:0071347 | Cellular response to interleukin-1 | 16.88289078 | 1.09298E−08 |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | 3.652056561 | 1.27896E−08 |
| GO:0014070 | Response to organic cyclic compound | 6.26379716 | 3.29652E−08 |
| GO:0008285 | Negative regulation of cell proliferation | 5.262199724 | 5.94266E−08 |
| GO:0033590 | Response to cobalamin | 90.04208417 | 6.01314E−08 |
| GO:0042493 | Response to drug | 4.287718294 | 6.34324E−08 |
| GO:0006468 | Protein phosphorylation | 4.846457788 | 8.88401E−08 |
| GO:0042542 | Response to hydrogen peroxide | 12.4673655 | 1.76279E−07 |
| GO:0009617 | Response to bacterium | 19.09983604 | 2.66E−07 |
| GO:0001889 | Liver development | 8.612721094 | 2.86336E−07 |
| GO:0001666 | Response to hypoxia | 5.58112092 | 4.40694E−07 |
| Downregulated GOs by GO analysis | |||
| GO:0045893 | Positive regulation of transcription, DNA-dependent | 3.77523152 | 3.05206E−07 |
| GO:0045892 | Negative regulation of transcription, DNA-dependent | 4.062477396 | 3.32485E−07 |
| GO:0016568 | Chromatin modification | 13.26523231 | 5.79738E−07 |
| GO:0043065 | Positive regulation of apoptotic process | 5.038731654 | 6.66823E−07 |
| GO:0008150 | Biological process | 2.365931438 | 1.86723E−06 |
| GO:0016572 | Histone phosphorylation | 46.4283131 | 3.08593E−06 |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | 2.954529015 | 4.94117E−06 |
| GO:0006355 | Regulation of transcription, DNA-dependent | 2.982729366 | 6.6796E−06 |
| GO:0003407 | Neural retina development | 36.11091019 | 1.08935E−05 |
| GO:0001525 | Angiogenesis | 5.879901494 | 1.29214E−05 |
| GO:0008284 | Positive regulation of cell proliferation | 3.559902873 | 3.26349E−05 |
| GO:0006950 | Response to stress | 5.762379285 | 4.3047E−05 |
| GO:0006915 | Apoptotic process | 3.631264712 | 4.68891E−05 |
| GO:0007165 | Signal transduction | 3.448256676 | 8.82113E−05 |
| GO:0043066 | Negative regulation of apoptotic process | 3.059606407 | 0.000134769 |