Table 1.

Clinical Characteristics of Included Surgical Patients

	Control	COPD	P Value
Number of patients	24	33	—
Age, yr	70.5 (61–76)	67 (60.5–74)	0.75*
M/F	12/12	16/17	0.91†
BMI, kg/m2	27.25 (22.63–31.55)	23.7 (21.25–28.95)	0.23*
Confirmed corticosteroid use, n	1	9	0.0336‡
Smoker, never/ex/current	6/15/3	1/20/12	0.0671‡
Pack-years of smoking	21 (0.625–52.5)	40 (31.25–62.5)	0.025*
FEV1%	98 (91.9–112)	76.13 (67–86)	<0.0001*
FEV1/FVC ratio	0.776 (0.73–0.805)	0.601 (0.551–0.654)	<0.0001*

Definition of abbreviations: BMI = body mass index; COPD = chronic obstructive pulmonary disease.

Data are presented as median (interquartile range) unless otherwise indicated. Ex-smokers were defined as individuals who had stopped smoking for more than 6 months before surgery. BMI data represent 16 control subjects and 17 patients with COPD. Comorbidity data are provided in Table E3.

^*Mann-Whitney U test.

^†χ² test.

^‡Fisher’s exact test.