Table 3.
Summary of Pathologic Classification of Miners with Rapidly Progressive Pneumoconiosis
| Miner | Source of Specimen | CWP* | Mixed Dust* | Silicosis† | PMF Present | Interstitial Fibrosis Grade | Predominant Disease Type |
|---|---|---|---|---|---|---|---|
| 1 | Explant | 0 | 3 | 2 | Yes | 2 | MD |
| 2 | Autopsy | 0 | 3 | 2 | Yes | 1 | MD |
| 3 | Autopsy | 0 | 3 | 2 | Yes | 3 | MD |
| 4* | Biopsy | 0 | 3 | 1 | No | 1 | MD |
| 5* | Biopsy | 0 | 3 | 3 | Yes | 1 | MD/silicosis‡ |
| 6 | Explant | 3 | 2 | 2 | Yes | 1 | MD/silicosis |
| 7* | Explant | 1 | 3 | 3 | Yes | 1 | MD/silicosis |
| 8* | Biopsy | 0 | 3 | 3 | Yes | 1 | MD/silicosis |
| 9 | Biopsy | 1 | 1 | 3 | Yes | 1 | Silicosis |
| 10* | Biopsy | 0 | 2 | 3 | Yes | 0 | Silicosis‡ |
| 11 | Biopsy | 3 | 1 | 1 | Yes | 0 | CWP |
| 12 | Explant | 0 | 0 | 0 | No | 3 | Nonspecific ILD |
| 13* | Explant | 0 | 0 | 0 | No | 3 | Nonspecific ILD |
| Total cases | 4 | 11 | 11 | 10 |
Definition of abbreviations: CWP = coal workers’ pneumoconiosis; ILD = interstitial lung disease; MD = mixed dust pneumoconiosis; PMF = progressive massive fibrosis.
Profusion category is given for each lesion type (range, 0–3). N = 13.
*
Sum of profusion scores for CWP and MD of macules and nodules. Maximum possible profusion score is 3.
†
Sum of profusion scores of silicotic nodules. Maximum possible profusion score is 3.
‡
Features of alveolar proteinosis present.