TABLE 1.
Ions that are significantly more intense in the cephalic ganglia
| Peptide | Mass |
p value |
Intensity ratio |
Relative error |
AUCc | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| KWa | ADb | 3 day/Intact | 6 day/Intact | 12 day/Intact | 3 day/Intact | 6 day/Intact | 12 day/Intact | |||
| dd_Smed_v4_1463_0_1 (ANTH-like domain) | 898.6 | 4.8 × 10−2 | 2.6 × 10−2 | 4 × 10−1 | 4 × 10−1 | 4 × 10−1 | 1 × 10−1 | 1 × 10−1 | 2 × 10−1 | 0.98 |
| SPP-4 [33–42]d | 1223.9 | 2.6 × 10−2 | 3.2 × 10−3 | 4 × 10−1 | 3 × 10−1 | 4 × 10−1 | 9 × 10−2 | 6 × 10−2 | 1 × 10−1 | 0.98 |
| EYE53-1 [30–42] | 1525.1 | 2.6 × 10−2 | 1.0 × 10−6 | 5 × 10−1 | 4 × 10−1 | 1 × 100 | 1 × 10−1 | 6 × 10−2 | 9 × 10−1 | 0.92 |
| SPP-6 [48–62] | 1590.0 | 2.3 × 10−2 | 1.0 × 10−4 | 3 × 10−1 | 4 × 10−1 | 1 × 100 | 8 × 10−2 | 1 × 10−1 | 4 × 10−1 | 1.00 |
| dd_Smed_v4_15196_0_1 (no SP)e | 1646.0 | 2.6 × 10−2 | 9.3 × 10−4 | 3 × 10−1 | 3 × 10−1 | 9 × 10−1 | 7 × 10−2 | 6 × 10−2 | 3 × 10−1 | 1.00 |
| SPP-12 [57–70] | 1884.1 | 2.6 × 10−2 | 2.7 × 10−3 | 2 × 10−1 | 3 × 10−1 | 7 × 10−1 | 4 × 10−2 | 9 × 10−2 | 3 × 10−1 | 1.00 |
| Not detected by HPLC-ESI MS/MS | 1901.1 | 3.8 × 10−2 | 1.5 × 10−2 | 4 × 10−1 | 5 × 10−1 | 7 × 10−1 | 6 × 10−2 | 2 × 10−1 | 2 × 10−1 | 1.00 |
| Smed_v4_1178_0_1 (SP)e | 1907.3 | 2.6 × 10−2 | 1.2 × 10−3 | 2 × 10−1 | 3 × 10−1 | 4 × 10−1 | 7 × 10−2 | 6 × 10−2 | 1 × 10−1 | 1.00 |
| Not detected by HPLC-ESI MS/MS | 2274.3 | 2.6 × 10−2 | 2.1 × 10−4 | 4 × 10−1 | 5 × 10−1 | 1 × 100 | 1 × 10−1 | 9 × 10−2 | 3 × 10−1 | 0.92 |
a p values calculated via the Kruskal-Wallis analysis of variance.
b p values calculated via the Anderson-Darling test for the normal distribution assumption.
c Area under the receiver operating characteristic curve.
d Amino acid positions in known prohormones are shown in brackets.
e Indicates the presence of signal peptide.