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. 2016 Feb 17;291(15):8150–8161. doi: 10.1074/jbc.M115.648717

FIGURE 10.

FIGURE 10.

Alignment of the PHs of PLCδ1, DGKη, DGKδ, and DGKκ. Lys-30, Lys-32, Arg-40, Ser-55, Arg-56, and Lys-57 in the PLCδ1-PH indicated by asterisks are important for strong PI(4,5)P2-selective binding activity. Lys-74 and Arg-85 in the DGKη-PH are indicated by red font.