Table 2.
Unadjusted and adjusted OR for elevated GDF-15 in patients with CAD undergoing PCI
| Variable | Unadjusted OR and 95th CI | P value | Adjusted OR and 95th CI | P value |
|---|---|---|---|---|
| Advanced age (>75 years) | 10.754 (6.003–19266) | <0.0001 | 8.262 (3.852–17.722) | <0.0001 |
| Female gender | 1.414 (0.958–2.087) | 0.081 | ||
| ACS diagnosis | 1.513 (1.045–2.191) | 0.028 | 0.912 (0.506–1.645) | 0.760 |
| AHG in patients with ACS | 3.297 (1.567–6.938) | 0.002 | 2.815 (1.070–7.403) | 0.036 |
| DM | 1.932 (1.286–2.903) | 0.002 | 2.210 (1.222–3.995) | 0.009 |
| Previous MI | 1.606 (1.060–2.432) | 0.025 | 1.514 (0.806–2.844) | 0.197 |
| CKD | 12.939 (6.071–27.574) | <0.0001 | 6.846 (2.858–16.400) | <0.0001 |
| NYHA ≥2 at presentation | 1.984 (1.050–3.746) | 0.035 | 1.647 (0.726–3.739) | 0.233 |
| Current smoking | 1.930 (1.284–2.901) | 0.002 | 0.903 (0.512–1.595) | 0.726 |
| Obesity (BMI >25 kg/m2) | 1.606 (1.050–2.455) | 0.029 | 2.184 (1.149–4.149) | 0.017 |
| Elevated CRP at admission | 1.831 (1.206–2.781) | 0.005 | 2.380 (1.377–4.114) | 0.002 |
OR odds ratio, CI confidence interval, ACS acute coronary syndrome, AHG acute hyperglycemia, DM diabetes mellitus, MI myocardial infarction, CKD chronic kidney disease, NYHA New York Heart Association, BMI body mass index, CRP high sensitive C-reactive protein