Table III.
N=44* | %Cumulative Incidence | Hazard Ratio (95% CI) | p-value |
---|---|---|---|
| |||
Acute GVHD II–IV | |||
MRD PB (n=9) | 56% (31–100) | 1.1 (0.2–5.9) | 0.9 |
MRD BM (n=5) | 40% (14–100) | Ref. | |
| |||
Acute GVHD III–IV | |||
MRD PB | 11% (2–70) | N/E | 0.5 |
MRD BM | 0% | ||
| |||
Acute GVHD II–IV | |||
MUD BM ATG (n=20) | 36% (21–68) | Ref. | |
MUD BM No ATG (n=10) | 80% (59–100) | 2.8 (1.1–7.5) | 0.03 |
| |||
Acute GVHD III–IV | |||
MUD BM ATG (n=20) | 10% (3–41) | Ref. | |
MUD BM No ATG (n=10) | 50% (27–93) | 3.1 (0.8–11) | 0.1 |
| |||
NRM 1-year | |||
MUD BM ATG (n=20) | 25% (12–53) | 0.4 | 0.25 |
MUD BM No ATG (n=10) | 40% (19–85) | Ref. |
3 patients who experienced primary graft failure were removed from the analysis, 2 MUD BM recipients and 1 MRD BM recipient. 2 MUD patients who received PB and ATG were removed from the analysis of the effect of ATG.