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. Author manuscript; available in PMC: 2016 Apr 8.
Published in final edited form as: JAMA Neurol. 2015 Aug;72(8):920–927. doi: 10.1001/jamaneurol.2015.0979

Figure 2. Immunoreactivity in the Hippocampus.

Figure 2

Four areas were assessed: cornu ammonis (CA) region 1 (CA1); the hilus or CA4; the parahippocampal gyrus (PHG), and white matter (WM). Groups are compared using a 2-tailed t test. The Alzheimer disease (AD) group indicates the patients with AD with normal TREM2 (n = 6); control, the nondemented cases (n = 3); and R47H_AD, patients with AD who carry TREM2 R47H (n = 7). All R47H_AD individuals and 3 of 6 AD group individuals are from the LOAD123 family; the others are sporadic cases. Iba1 indicates ionized calcium-binding adapter molecule 1; MHCII, major histocompatibility complex class II. The error bars indicate 1 SD.

aP < .05.