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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Hypertension. 2015 Jul 6;66(3):534–542. doi: 10.1161/HYPERTENSIONAHA.115.05320

Figure 7. The absence of renal ACE amplifies reductions in abundance and/or phosphorylation of NCC and the cleaved (CL) portion of αENaC after 3 weeks of a high salt diet.

Figure 7

(A) Transporter expression was analyzed in total kidney homogenates from non-treated mice and after a 3-week high salt phase. L-NAME was given to wild-type (0.5 mg/mL) and mutant mice (1.5 mg/mL) in the drinking water. Immunoblots were performed with a constant amount of protein per lane. Relative abundance from each group is displayed below the corresponding blot as mean ± SEM. n = 12 per group, *p<0.05; **p<0.01; ***p<0.001 vs. corresponding non-treated mice. (B) Bars represent the relative reduction vs. non-treated mice (set as 0), *p<0.05; **p<0.01; ***p<0.001.