Table 1.
No | Year/1st author/ref.no |
Study population | Inclusion criteria |
Exclusion criteria | Total number analyzed |
Prep | N per group |
Mean age |
Male/ Female |
Unable to complete prep (%) |
Prep Quality |
Conclusions |
|||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Excellent (%) |
Good (%) |
Exce / Good (%) |
Prep Quality |
Prep Completion |
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1 | Vanner 199014 | Consecutive patients for elective colonoscopy | Polyps 56%, IBD 12%, bleeding 3%, others 29 % | Creatinine 2.3 mg/dL, symptomatic CHF, massive ascites, MI within 6 months | 102 | NaP sol | 54 | 52 | 30/24 | 0 | 26 | 54 | 80 | NaP better | NaP better |
4L PEG | 48 | 58 | 25/23 | 20 | 6 | 27 | 33 | ||||||||
| |||||||||||||||
2 | Kolts 199315 | Consecutive outpatients | Polyps 45%, GI bleed 32%, anemia 4%, diarrhea 4%, constipation 4%, other 11% | Unstable CV status, MI, CVA < 2 mo, creatinine > 2 mg/dL, massive ascites, active IBD, active diverticulitis, delayed gastric emptying | 72 | NaP sol | 34 | 52 | 7/27 | 1 | 38 | 41 | 79 | NaP better | NaP=PEG |
4L PEG | 38 | 58 | 20/18 | 5 | 32 | 29 | 61 | ||||||||
| |||||||||||||||
3 | Marshall 199329 | Consecutive, non-emergent patients | Not stated | Symptomatic CHF, recent MI, creatinine ≥ 2.3 mg/dL, ascites | 143 | NaP sol | 70 | 57.2 | 64/79 for both groups | 13 | 39 | 30 | 69 | NaP=PEG | NaP=PEG |
4L PEG | 73 | 57.2 | 18 | 47 | 23 | 70 | |||||||||
| |||||||||||||||
4 | Cohen 199416 | Elective colonoscopy; age/sex–matched | Not stated | Not stated | 422 | NaP sol | 143 | 66.5 | 74/69 | 3 | 65 | 25 | 90 | NaP better | NaP better |
4L PEG | 279 | 66.7 | 141/138 | 28 | 43 | 25 | 68 | ||||||||
| |||||||||||||||
5 | Golub 1995†36 | Consecutive, ambulatory patients matched for age/sex/indication | Polyps 62%, bleeding 15%, cancer 13%, family history 3%, other 8% | Not stated | 230 | NaP sol | 106 | 58.4 | NA | 1 | 46 | 43 | 89 | NaP=PEG | NaP better |
4L PEG | 124 | 58.4 | NA | 15 | 48 | 37 | 85 | ||||||||
| |||||||||||||||
6 | Chia 199531 | Elective colonoscopy | Not stated | > 60 years of age, pregnant, history of renal or cardiac diseases, acute IBD and intestinal obstruction | 79 | NaP sol | 39 | 47.7 | 20/19 | Not specified | Not specified | Not specified | 85 | NaP better | NaP=PEG |
4L PEG | 40 | 53.2 | 15/25 | 63 | |||||||||||
| |||||||||||||||
7 | Henderson 199532 | Outpatient, elective colonoscopies | Not stated | Symptomatic CHF, recent MI, creatinine > 2 mg/dL, ascites | 157 | NaP sol | 51 | 51 | 107/111 for both groups | 1 | Not specified | Not specified | 91 | NaP=PEG | NaP better |
4L PEG | 106 | 51 | 10 | 92 | |||||||||||
| |||||||||||||||
8 | Thompson 199628 | Outpatient colonoscopy | Not stated | Ischemic chest pain, MI, TIA/CVA in last 6 months, creatinine > 200 μg/L, ascites, CHF, colostomy, AMS | 116 | NaP sol | 61 | 72 | 47/14 | 3 | 20 | 46 | 66 | NaP better | NaP better |
4L PEG | 55 | 70 | 38/17 | 2 | 15 | 44 | 58 | ||||||||
| |||||||||||||||
9 | Clarkston 199627 | Outpatient colonoscopy | Not stated | Severe CHF, creatinine ≥ 2.3 mg/dL, prior bowel resection | 98 | NaP sol | 49 | 57 | 22/27 | 4 | 45 | 36 | 81 | NaP=PEG | NaP=PEG |
4L PEG | 49 | 57 | 12/37 | 27 | 31 | 50 | 81 | ||||||||
| |||||||||||||||
10 | Lee 199926 | Consecutive outpatients | Not stated | Not stated | 159 | NaP sol | 71 | 51.5 | 79/80 | 4 | 40 | 31 | 71 | NaP=PEG | NaP better |
4L PEG | 88 | 57.9 | for all | 11 | 43 | 31 | 74 | ||||||||
| |||||||||||||||
11 | Aronchick 20009 | Outpatient colonoscopy | Not stated | CHF, chronic renal failure, megacolon, severe constipation, partial or subtotal colectomy, or pre-existing electrolyte abnormalities. | 206 | NaP sol | 106 | 60.3 | 46/60 | 1 | 77 | 9 | 86 | NaP=PEG | NaP better |
4L PEG | 100 | 58.8 | 52/48 | 12 | 66 | 16 | 82 | ||||||||
| |||||||||||||||
12 | Arezzo 200030 | Consecutive patients | Not stated | Not stated | 200 | NaP sol | 100 | 61.9 | 45/55 | Not specified | Not specified | Not specified | 68 | NaP better | NaP=PEG |
4L PEG | 100 | 60.5 | 52/48 | 50 | |||||||||||
| |||||||||||||||
13 | Seinela 200325 | Consecutive patients | Age > 80 years | Creatinine 2.3 mg/dL, CHF, massive ascites, MI, bowel resection | 72 | NaP sol | 37 | 84 | 1o/62 | Not specified | 48 | 33 | 81 | NaP=PEG | NaP=PEG |
4L PEG | 35 | 84 | for all | 52 | 26 | 78 | |||||||||
| |||||||||||||||
14 | Law 2004¶24 | Elective colonoscopy | Age > 18 years | Intestinal obstruction, delayed gastric emptying, creatinine >0.2 mmol/L, CHF, MI in the last 6 months, massive ascites and pregnancy. | 207 | NaP sol | 101 | 58.1 | NA | Not specified | 15 | 50 | 65 | NaP better | NaP better |
4L PEG | 106 | 58.1 | NA | 12 | 47 | 59 | |||||||||
| |||||||||||||||
15 | Hwang 200523 | Elective colonoscopy | Not stated | Symptomatic CHF, MI, creatinine >1.5 mg/dL, abnormal elevation of transaminases, ileus, bowel obstruction, gastric retention, uncontrolled HTN, unstable angina, pregnancy or breast feeding and severe constipation. | 78 | NaP sol | 38 | 52.2 | 18/22 | Not specified | 58 | 21 | 79 | NaP=PEG | NaP=PEG |
4L PEG | 40 | 52.4 | 25/15 | 55 | 28 | 83 | |||||||||
| |||||||||||||||
16 | Bektas 200533 | Elective colonoscopy | Not stated | Creatinine > 2 mg/dL, pregnancy, bowel obstruction, symptomatic CHF, MI in last 3 months, emergent colonoscopy, acute IBD, ascites | 97 | NaP sol | 61 | 56.7 | 29/32 | Not specified | 52 | 38 | 90 | NaP=PEG | NaP better |
4L PEG | 36 | 54.3 | 13/23 | 47 | 44 | 91 | |||||||||
| |||||||||||||||
17 | Huppertz-Hauss 2005¶34 | Consecutive outpatients for colonoscopy | Not stated | < 18 years, creatinine> 150mmol/L, CHF, hepatic failure, electrolyte abnormalities, | 160 | NaP sol | 84 | 58.6 | 43/41 | Not specified | Not specified | Not specified | 85 | NaP=PEG | NaP=PEG |
4L PEG | 76 | 57.4 | 29/47 | 81 | |||||||||||
| |||||||||||||||
18 | Rostom 2006†35 | Elective colonoscopy | patients 18-80 years old | Renal failure, unstable angina, acute coronary syndrome, CHF, ascites, megacolon, bowel obstruction, previous bowel resection and evaluation of diarrhea | 194 | NaP sol | 144 | 52 | 39/95 | 8 | Data presented as mean scores | NaP better | NaP better | ||
4L PEG | 50 | 55 | 16/34 | 21 |
Congestive heart failure-CHF, Myocardial infarction -MI, Acute coronary syndrome-ACS, Hypertension-HTN, Inflammatory bowel diseases-IBD, Altered mental status-AMS, Transient ischemic attack-TIA, Cerebrovascular attack-CVA.
Trials not included in prep completion analysis as there was no data available.
Trials not included in prep quality analysis as the data was either presented as mean scores or not available.