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. 2015 Oct 27;14(22):3613–3623. doi: 10.1080/15384101.2015.1100777

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Figure 7. — NML expression is downregulated in a subset of tumors. (A) Reduced NML gene (RRP8) copy number in a bladder cancer cohort (Oncomine). A subset of tumor samples showed heterozygous deletion at the RRP8 locus. (B) Reduced NML mRNA level in an invasive breast cancer cohort compared to normal tissue (Oncomine). (C, D) Kaplan-Meyer plots of 3450 patients with breast tumors following systemic treatment showing that low NML (RRP8, probe set 203170_at) and TIP5 (TIP5, probe set 201355_s_at) mRNA levels are associated with shorter relapse free survival.