Skip to main content
. 2015 May 6;14(24):3939–3953. doi: 10.1080/15384101.2015.1044177

Figure 8.

Figure 8.

Working model: The consequence of DEK overexpression in mitosis. (A) A schematic detailing the various stages of mitosis including the loss of DEK association with chromatin in prophase and re-association in telophase. (B) The over-expression of DEK leads to its aberrant retention on mitotic chromosomes throughout mitosis. The end result is malsegregated chromosomes that end up as micronuclei in daughter cells.