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SCI-induced upregulation of cell cycle-relayed proteins at lesion site was significantly attenuated by intrathecal injection of E2Fs decoy oligodeoxynucleotides (ODNs) at day 1 post-injury. (A) Representative western blots of cell cycle-related proteins including E2F1, E2F2, CDK1, and PCNA. (B) Quantification of western blot from A. Veh: Vehicle; SC: scrambled ODN; ODNs: E2Fs ODNs. n=3-5 mice/group. *p <0.05, **p<0.01, ***p< 0.001 vs. sham group; #p<0.05, ##p<0.01 versus SC group.
