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. Author manuscript; available in PMC: 2016 Apr 8.
Published in final edited form as: Biomacromolecules. 2015 Nov 19;16(12):3845–3852. doi: 10.1021/acs.biomac.5b01162

Table 2.

Minimum Inhibitory Concentrations (MIC) Values (μg/mL) of AMP-Mimics Determined by Microbroth Dilution Method (24 h) with Different Media and Buffersa

MIC (μg/mL)
MHB (Tris buffer)
 MHB (TBS buffer)
 low salt LB (Tris buffer)
polymer E. coli S. aureus P. aeruginosa E. coli S. aureus P. aeruginosa E. coli S. aureus P. aeruginosa
PAPMA 125 250 250 500 500 500 250 500 500
PGT25 250 500 750 1000 1000 1000 250 500 500
PGT50 1000 1000 1000 >1000 >1000 >1000 500 750 750
PGT75 1000 1000 1000 >1000 >1000 >1000 500 750 1000
PGT100 1000 1000 1000 >1000 >1000 >1000 500 750 1000
a

MIC = concentration of (co)polymer required to completely inhibit bacterial growth. Experiments performed in triplicate with three replications.