Table 1.
Country, institution | ||||||
---|---|---|---|---|---|---|
| ||||||
Guidelines parameter | Spain, GesEPOC | Czech Republic, CPPS | Finland, FMSD/FRS | India, Indian Chest Society/NCCP | Saudi Arabia, STS | Global, GOLD |
Guided by | Phenotypes alone | GOLDa and phenotypes | GOLDb and phenotypes | GOLD and phenotypesc | Three phenotypic classesd | GOLD alone |
Mainly focused on | GPs + PFs | PFs | GPs | GPs | GPs + INs + PFs | GPs + PFs |
Valid since | 2012 | 2013 | 2014 | 2013 | 2014 | 2015 |
Spirometry post-BD | Mandatory | Mandatory | Mandatory | Mandatory | Mandatory | Mandatory |
Airflow limitation definition | FEV1/FVC <0.7 | FEV1/VC <LLN | FEV1/FVC <0.7 | FEV1/FVC <LLNe | FEV1/FVC <0.7 | FEV1/FVC <0.7 |
Frequent exacerbator means | ≥2/year | ≥2/year | ≥2/year or ≥1/year leading to hospital admission | ≥2/year | ≥2/year or ≥1/year leading to hospital admission | ≥2/year or ≥1/year leading to hospital admission |
High level of symptoms | CAT ≥10 (mMRC scale ≥2) | CAT ≥10 (mMRC scale ≥1) | CAT ≥10 | mMRC scale ≥2 (CAT ≥10) | CAT ≥10 | CAT ≥10 or mMRC scale ≥2 |
Smoking cessation | Mandatory | Mandatory | Mandatory | Mandatoryf | Mandatoryg | Mandatory |
BD’s role | Mandatory | Mandatory | Mandatory | Mandatory, short-acting only, long-acting for moderate and severe categories | Mandatory | Mandatory |
ICS role | FAEs or ACOS | FAEs or ACOS | FAEs or ACOS | Severe category | FAEs (Class III) | C and D categories |
Mucoactive drugs’ role | FAEs | FAEs with chronic bronchitis, or BCOS | FAEs | NR | Optional | D category |
Long-term ATB role | FAEs with chronic bronchitis | FAEs with chronic bronchitis or with BCOS | NR | NR | NR | NR |
Methylxanthines role | Optional | Optional | Optional | Optional | Optional | Optional |
Roflumilast role | FAEs with chronic bronchitis and FEV1 <50% | FAEs with chronic bronchitis and FEV1 <50% | FAEs with chronic bronchitis and FEV1 <50% | Severe category | FAEs with chronic bronchitis (Class III) | D GOLD category with chronic bronchitis and FEV1 < 50% |
Training of inhalation | Mandatory | Mandatory | Mandatory | Mandatory | Mandatory | Mandatory |
Regular physical activity | Mandatory | Mandatory | Mandatory | Mandatory | Mandatory | Mandatory |
Influenza and pneumococcal vaccination | Mandatory | Mandatory | Mandatory | Optional | Mandatory | Mandatory |
Notes:
Czech guidelines use slightly modified GOLD categories.
Finnish guidelines use GOLD 1–4 grading (according to post-BD FEV1).
Classification of severity of the disease (into three categories) should be done for all COPD patients based on the post-BD FEV1, exacerbation frequency, mMRC dyspnea scale, and presence of respiratory failure/cor pulmonale/secondary polycythemia.
Those patients with low risk of exacerbation (less than two in the past year) can be classified as either Class I when they have less symptoms or Class II when they have more symptoms (CAT ≥10). High-risk COPD patients, as manifested with more than or equal to two exacerbations or hospitalization in the past year irrespective of the baseline symptoms, are classified as Class III.
In the absence of reference equations for LLN, FEV1/FVC <0.7 may be used as the cutoff for defining airflow obstruction.
Included Bidi and other indigenous forms of tobacco smoking; exposure to biomass fuel smoke is a strong risk factor for COPD in India.
Included shisha (water pipe). Data from GOLD,1 Miravitlles et al,17 Kankaanranta et al,51 Gupta et al,52 Khan et al,53 and Koblizek et al.54
Abbreviations: ACOS, asthma and COPD overlap; ATBs, antibiotics; BCOS, bronchiectasis and COPD overlap syndrome; BD, bronchodilator; CAT, COPD Assessment Test; CPPS, Czech Pneumological and Phthisiological Society; FAEs, frequent acute exacerbators; FEV1, forced expiratory volume in 1 second; FMSD, Finnish Medical Society Duodecim; FRS, Finnish Respiratory Society; FVC, forced volume vital capacity; GesEPOC, La Guía Española de la EPOC (Spanish COPD Guidelines); GOLD, Global Initiative for Chronic Obstructive Lung Disease; GPs, general practitioners; ICS, inhaled corticosteroids; INs, internists; LLN, the lower limit of normal; mMRC, modified Medical Research Council; NCCP, National College of Chest Physicians (India); NR, not recommended; PFs, pulmonary physicians; STS, Saudi Thoracic Society; VC, vital capacity.