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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Virology. 2016 Feb 11;491:79–88. doi: 10.1016/j.virol.2016.01.015

Table 3.

Mean percentage macroscopic pneumonia, composite microscopic pneumonia, and trachea microscopic scores ± standard error of the mean (SEM) from pigs with maternally-derived antibodies (MDA) from exposed sows vaccinated with H1N1pdm09 whole inactivated virus (WIV-MDA) vaccine or experimentally infected with H1N1pdm09 (EXP-MDA), or from a non-boosted naturally exposed sow (NAT-MDA), or without MDA (No MDA) at 5 days post infection (dpi) with homologous H1N1pdm09(2:6) or heterologous H1N2-δ1(1:7) in Study 2.

Challenge Groups Macroscopic percentage (%) Microscopic scores (0-22) Trachea histopathology (0-8)
Homologous
No MDA/NC 0.4 ± 0.1a 1.3 ± 0.1a 0.1 ± 0.1a
No MDA/H1N1 24.6 ± 2.3b 15.2 ± 0.6b 17 ± 03b,c
WIV-MDA/H1N1 0.7 ± 0.4a,c 5.3 ± 0.1c 0.8 ± 0.6a,b
EXP-MDA/H1N1 8.2 ± 1.8c 10.4 ± 0.9d 2.4 ± 0.2c
Heterologous
No MDA/NC 0.4 ± 0.1a 1.3 ± 0.1a 0.1 ± 0.1a
No MDA/H1N2 15.2 ± 2.0b 13.4 ± 0.7b 3.1 ± 0.5b
WIV-MDA/H1N2 28.9 ± 8.1c 13.4 ± 1.0b 3.0 ± 0.6b
EXP-MDA/H1N2 17.6 ± 2.0b,c 12.0 ± 0.8b 2.3 ± 0.4b
NAT-MDA/H1N2 16.2 ± 2.9b 17.7 ± 1.1c 3.5 ± 0.6b
a,b,c

Statistically significant differences in the same column identified with different lowercase letters (P ≤ 0.05).