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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Virology. 2016 Feb 11;491:79–88. doi: 10.1016/j.virol.2016.01.015

Table 5.

Virus titers in nasal swabs from pigs with maternally-derived antibodies (MDA) from exposed sows vaccinated with H1N1pdm09 whole inactivated virus (WIV-MDA) vaccine or experimentally infected with H1N1pdm09 (EXP-MDA), or from a non-boosted H1N1pdm09 naturally exposed sow (NAT-MDA), and without MDA (No MDA) at 1 to 5 days post infection (dpi) with homologous H1N1pdm09(2:6) or heterologous H1N2-δ1(1:7) in Study 2. Values shown as mean ± standard error of the mean (SEM).

Challenge Groups Nasal swabsx BALFx

1 dpi 2 dpi 3 dpi 4 dpi 5 dpi 5 dpi
No MDA/NC 0.0 ± 0.0a 0.0 ± 0.0a 0.0 ± 0.0a 0.0 ± 0.0a 0.0 ± 0.0a 0.0 ± 0.0a
Homologous
No MDA/H1N1 1.2 ± 0.3b 1.1 ± 0.2b 1.7 ± 0.2b 2.3 ± 0.2b 1.0 ± 0.2b 4.2 ± 0.3b
WIV-MDA/H1N1 0.0 ± 0.0a 0.1 ± 0.1a 0.0 ± 0.0a 0.1 ± 0.1a 0.1 ± 0.1a 0.0 ± 0.0a
EXP-MDA/H1N1 0.0 ± 0.0a 0.6 ± 0.3a,b 0.6 ± 0.4a 0.7 ± 0.3a 0.4 ± 0.1a,b 3.7 ± 0.6b
Heterologous
No MDA/H1N2 2.8 ± 0.3b 2.6 ± 0.2b 3.3 ± 0.3b 3.1 ± 0.2b 3.0 ± 0.2b 5.1 ± 0.3b
WIV-MDA/H1N2 2.5 ± 0.6b 2.1 ± 0.4b 3.0 ± 0.3b 2.9 ± 0.2b 1.6 ± 0.4c 6.0 ± 0.2b,c
EXP-MDA/H1N2 2.8 ± 0.4b 2.6 ± 0.5b 3.0 ± 0.2b 2.7 ± 0.3b 2.8 ± 0.4b 6.8 ± 0.2c
NAT-MDA /H1N2 1.1 ± 0.5c 3.1 ± 0.4b 2.3 ± 0.4b 2.8 ± 0.1b 2.5 ± 0.4b,c 6.1 ± 0.2b,c
x

Virus titers represented as log10 TCID50/ml.

a,b,c

Statistically significant differences identified with different lowercase letters (P ≤ 0.05).