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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Clin Cancer Res. 2015 Oct 21;22(5):1161–1172. doi: 10.1158/1078-0432.CCR-15-1516

Figure 5. Combining focal RT with vaccination improves survival in mice with established CNS melanoma.

Figure 5

(A) Combination treatment with focal RT + TGF-β1 signaling inhibition (B) Combination treatment with focal RT + LM-based vaccine (C) CD3 immunofluorescence in brain sections from treated mice at 20×. (D) Representative H&E micrographs of brain tissue from mice with treated brain tumors at 20× (top row) and 40× (bottom row). (E) Representative ex vivo MRI slices from mice with treated brain tumors. Experiments performed × 3 with 10 mice/group, typical results shown.