Table 4. Subtypes and maturation markers of dendritic cells (expressed as percentages) in current and former smokers non-COPD by flow cytometry.
DC subtype | Maturationmarker | Current smokers(n = 11) | Former smokers(n = 13) | P value* |
---|---|---|---|---|
BDCA1+ mDCs | CD40 | 1.3 (1.9) | 20.8 (32.0) | 0.036 |
CD80 | 13.4 (22.0) | 15.3 (23.4) | NS | |
CD83 | 1.6 (5.0) | 17.3 (30.3) | NS | |
CD86 | 13.0 (15.4) | 14.3 (19.3) | 0.011 | |
BDCA3+ mDCS | CD40 | 3.1 (10.12) | 13.5 (29.3) | NS |
CD80 | 7.8 (24.1) | 15.4 (25.2) | NS | |
CD83 | 5.8 (13.9) | 13.3 (27.9) | NS | |
CD86 | 3.0 (9.1) | 20.5 (32.9) | 0.034 | |
pDCs | CD40 | 0.9 (2.42) | 11.4 (28.7) | NS |
CD80 | 10.8 (19.1) | 13.4 (25.8) | NS | |
CD83 | 3.2 (8.3) | 17.2 (32.8) | NS | |
CD86 | 7.3 (10.9) | 7.5 (12.5) | NS |
* Mann–Whitney U-test. N/A: not applicable; NS: not significant